Development and in-vitro, in-vivo evaluation of Pioglitazone-loaded polymeric nanoparticles using central composite design surface response methodology

Development and in-vitro, in-vivo evaluation of Pioglitazone-loaded polymeric nanoparticles using central composite design surface response methodology

Pioglitazone is a type 2 diabetes drug encapsulated in polymeric nanoparticles using solvent evaporation techniques. In this study, the drug-polymer ratio (A), stirring speed (B), and stirring time (C) were three process parameters that were optimized using a three-factor, three-level Central Compos...

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Bibliographic Details
Main Authors: Dinesh Kumar Sharma, Gurudutta Pattnaik, Amulyaratna Behera
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:OpenNano
Subjects:
Pioglitazone
Nanoparticle
Chitosan
PEG
PLGA
Central composite design
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952023000208

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