Oxidative stress battles neuronal Bcl-xL in a fight to the death

Oxidative stress battles neuronal Bcl-xL in a fight to the death

Bcl-xL is a pro-survival protein of the Bcl2 family found in the mitochondrial membrane. Bcl-xL supports growth, development, and maturation of neurons, and it also prevents neuronal death during neurotoxic stimulation. This article reviews the mechanisms and upstream signaling that regulate the act...

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Bibliographic Details
Main Authors: Han-A Park, Katheryn Broman, Elizabeth A Jonas
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
atp; bcl-xl; f1fo atp synthase; mitochondria; neuroprotection; oxidative stress
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=1;spage=12;epage=15;aulast=Park

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=1;spage=12;epage=15;aulast=Park

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