Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity

Natural Killer cells are key mediators of anti-tumour immunosurveillance and anti-viral immunity. Here, the authors map regulatory genetic variation in primary Natural Killer cells, providing new insights into their role in human health and disease.

Bibliographic Details
Main Authors: James J. Gilchrist, Seiko Makino, Vivek Naranbhai, Piyush K. Sharma, Surya Koturan, Orion Tong, Chelsea A. Taylor, Robert A. Watson, Alba Verge de los Aires, Rosalin Cooper, Evelyn Lau, Sara Danielli, Dan Hameiri-Bowen, Wanseon Lee, Esther Ng, Justin Whalley, Julian C. Knight, Benjamin P. Fairfax
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31626-4