Genome-Wide Profiling Reveals HPV Integration Pattern and Activated Carcinogenic Pathways in Penile Squamous Cell Carcinoma

Genome-Wide Profiling Reveals HPV Integration Pattern and Activated Carcinogenic Pathways in Penile Squamous Cell Carcinoma

Human papillomavirus (HPV) is a significant etiologic driver of penile squamous cell carcinoma (PSCC). The integration pattern of HPV and its carcinogenic mechanism in PSCC remain largely unclear. We retrospectively reviewed 108 PSCC cases who received surgery between 2008 and 2017. Using high-throu...

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Bibliographic Details
Main Authors: Kang-Bo Huang, Sheng-Jie Guo, Yong-Hong Li, Xin-Ke Zhang, Dong Chen, Philippe E. Spiess, Zai-Shang Li, Chuang-Zhong Deng, Jie-Ping Chen, Qiang-Hua Zhou, Zheng Hu, Xin Ma, Jie-Tian Jin, Yun Cao, Jun-Hang Luo, Xiao-Bin Wang, Fang-Jian Zhou, Ran-Yi Liu, Hui Han
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
penile squamous cell carcinoma
human papillomavirus
E2
MAPK signaling pathway
CADM2
Online Access:https://www.mdpi.com/2072-6694/13/23/6104

Internet

https://www.mdpi.com/2072-6694/13/23/6104

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