Cell surface marker-based capture of neoantigen-reactive CD8+ T-cell receptors from metastatic tumor digests

Cell surface marker-based capture of neoantigen-reactive CD8+ T-cell receptors from metastatic tumor digests

Background Cellular immunotherapies using autologous tumor-infiltrating lymphocytes (TIL) can induce durable regression of epithelial cancers in selected patients with treatment-refractory metastatic disease. As the genetic engineering of T cells with tumor-reactive T-cell receptors (TCRs) comes to...

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Bibliographic Details
Main Authors: Steven A Rosenberg, Paul Robbins, Biman Paria, Jared J Gartner, Sri Krishna, Satyajit Ray, Rami Yossef, Victoria Hill, Frank J Lowery, Praveen D Chatani, Neilesh B Parikh, Kyle J Hitscherich, Maria Florentin, Alakesh Bera, Maria Parkhust
Format: Article
Language:English
Published: BMJ Publishing Group 2023-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/5/e006264.full

Internet

https://jitc.bmj.com/content/11/5/e006264.full

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