Clic4, a novel protein that sensitizes β-cells to apoptosis

Objectives: Chloride intracellular channel protein 4 (Clic4) is a ubiquitously expressed protein involved in multiple cellular processes including cell-cycle control, cell differentiation, and apoptosis. Here, we investigated the role of Clic4 in pancreatic β-cell apoptosis. Methods: We used βTC-tet...

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Bibliographic Details
Main Authors: Dhaval Patel, Damien Ythier, Flora Brozzi, Decio L. Eizirik, Bernard Thorens
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877815000046