Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components.

Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components.

Dengue virus (DENV) is the most prevalent, medically important mosquito-borne virus. Disease ranges from uncomplicated dengue to life-threatening disease, characterized by endothelial dysfunction and vascular leakage. Previously, we demonstrated that DENV nonstructural protein 1 (NS1) induces endoth...

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Bibliographic Details
Main Authors: Dustin R Glasner, Kalani Ratnasiri, Henry Puerta-Guardo, Diego A Espinosa, P Robert Beatty, Eva Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5679539?pdf=render

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http://europepmc.org/articles/PMC5679539?pdf=render

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