A fluorogenic substrate for the detection of lipid amidases in intact cells

A fluorogenic substrate for the detection of lipid amidases in intact cells

Lipid amidases of therapeutic relevance include acid ceramidase (AC), N-acylethanolamine-hydrolyzing acid amidase, and fatty acid amide hydrolase (FAAH). Although fluorogenic substrates have been developed for the three enzymes and high-throughput methods for screening have been reported, a platform...

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Bibliographic Details
Main Authors: Mireia Casasampere, Johnson Ung, Alejandro Iñáñez, Carine Dufau, Kazuhito Tsuboi, Josefina Casas, Su-Fern Tan, David J. Feith, Nathalie Andrieu-Abadie, Bruno Segui, Thomas P. Loughran, Jr., José Luis Abad, Gemma Fabrias
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of Lipid Research
Subjects:
sphingolipids
ceramides
lipids
enzymology
chemical synthesis
N-palmitoylethanolamine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524000257

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http://www.sciencedirect.com/science/article/pii/S0022227524000257

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