Extensive variation in gene copy number at the killer immunoglobulin-like receptor locus in humans.

Extensive variation in gene copy number at the killer immunoglobulin-like receptor locus in humans.

Killer immunoglobulin-like receptors (KIRs) are involved in the regulation of natural killer cell cytotoxicity. Within the human genome seventeen KIR genes are present, which all contain a large number of allelic variants. The high level of homology among KIR genes has hampered KIR genotyping in lar...

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Bibliographic Details
Main Authors: Sanne Vendelbosch, Martin de Boer, Remko A T W Gouw, Cynthia K Y Ho, Judy Geissler, Wendy T N Swelsen, Michael J Moorhouse, Neubury M Lardy, Dirk Roos, Timo K van den Berg, Taco W Kuijpers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3695908?pdf=render

Internet

http://europepmc.org/articles/PMC3695908?pdf=render

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