Reduction of MTT by Glutathione S-Transferase
The reduction of the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) to a blue formazan product is widely used for assaying cell survival and proliferation. The reduction reaction is catalyzed by dehydrogenases localized in the mitochondria of viable cells. As pa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
1998-10-01
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| Series: | BioTechniques |
| Online Access: | https://www.future-science.com/doi/10.2144/98254st03 |