GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration after optic nerve crush in mice

GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration after optic nerve crush in mice

Glaucoma is an optic neuropathy and is currently one of the most common diseases that leads to irreversible blindness. The axonal degeneration that occurs before retinal ganglion neuronal loss is suggested to be involved in the pathogenesis of glaucoma. G protein-coupled receptor 3 (GPR3) belongs to...

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Bibliographic Details
Main Authors: Shun Masuda, Shigeru Tanaka, Hiroko Shiraki, Yusuke Sotomaru, Kana Harada, Izumi Hide, Yoshiaki Kiuchi, Norio Sakai
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Neurobiology of Disease
Subjects:
GPR3
cAMP
Axonal regeneration
Retinal granular cells
Neuronal survival
Optic nerve injury
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996122002030

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http://www.sciencedirect.com/science/article/pii/S0969996122002030

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