Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease.

Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease.

The molecular bases of Alzheimer's disease (AD) remain unclear. We used a lipidomic approach to identify lipid abnormalities in the brains of subjects with AD (N = 37) compared to age-matched controls (N = 17). The analyses revealed statistically detectable elevations in levels of non-esterifie...

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Bibliographic Details
Main Authors: Giuseppe Astarita, Kwang-Mook Jung, Vitaly Vasilevko, Nicholas V Dipatrizio, Sarah K Martin, David H Cribbs, Elizabeth Head, Carl W Cotman, Daniele Piomelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3202527?pdf=render

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http://europepmc.org/articles/PMC3202527?pdf=render

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