Development and evaluation of a pseudovirus-luciferase assay for rapid and quantitative detection of neutralizing antibodies against enterovirus 71.

Development and evaluation of a pseudovirus-luciferase assay for rapid and quantitative detection of neutralizing antibodies against enterovirus 71.

The level of neutralizing antibodies (NtAb) induced by vaccine inoculation is an important endpoint to evaluate the efficacy of EV71 vaccine. In order to evaluate the efficacy of EV71 vaccine, here, we reported the development of a novel pseudovirus system expression firefly luciferase (PVLA) for th...

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Bibliographic Details
Main Authors: Xing Wu, Qunying Mao, Xin Yao, Pan Chen, Xiangmei Chen, Jie Shao, Fan Gao, Xiang Yu, Fengcai Zhu, Rongcheng Li, Wenhui Li, Zhenglun Liang, Junzhi Wang, Fengmin Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3673970?pdf=render

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http://europepmc.org/articles/PMC3673970?pdf=render

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