MHC-identical and transgenic cynomolgus macaques for preclinical studies

MHC-identical and transgenic cynomolgus macaques for preclinical studies

Abstract Cynomolgus macaques are useful experimental animals that are physiologically and genetically close to humans. We have developed two kinds of experimental usage of cynomolgus macaque: transplantation and disease models. First, we identified certain major histocompatibility complex (MHC) hapl...

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Bibliographic Details
Main Authors: Hirohito Ishigaki, Takashi Shiina, Kazumasa Ogasawara
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Inflammation and Regeneration
Subjects:
Cynomolgus macaque
Transplantation
MHC-homozygous
iPSC
Genetically modified macaque
Online Access:http://link.springer.com/article/10.1186/s41232-018-0088-3

Internet

http://link.springer.com/article/10.1186/s41232-018-0088-3

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