Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model

Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and in autoradiograms from 6-hydroxydopamine (6-OHDA) rat. In both species, acute levodopa administration was associated with increases in basal gangl...

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Bibliographic Details
Main Authors: Renata P. Lerner, Zisis Bimpisidis, Stergiani Agorastos, Sandra Scherrer, Stephen L. Dewey, M. Angela Cenci, David Eidelberg
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116301978