Putative role of HLA polymorphism among a Brazilian HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) population

Abstract Around ten million people are infected with HTLV-1 worldwide, and 1–4% develop HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), characterized by an important degeneration of the spinal cord, which can lead to death. Distinct HLA alleles have been associated with either H...

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Bibliographic Details
Main Authors: Doris Schor, Luís Cristóvão Porto, Eric Henrique Roma, Julio Castro-Alves, Anna Paula Villela, Abelardo Q. C. Araújo, Maria Glória Bonecini-Almeida
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34757-w