CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism

CD147 Mediates 5-Fluorouracil Resistance in Colorectal Cancer by Reprogramming Glycolipid Metabolism

Chemoresistance against 5-fluorouracil (5-FU) is a major issue for colorectal cancer (CRC) patients. Increasing evidence for the roles of CD147 in glycolipid metabolic reprogramming and chemoresistance of tumor cells has emerged in recent years. However, whether CD147 contributes to 5-FU resistance...

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Bibliographic Details
Main Authors: Shuohui Dong, Songhan Li, Xiaoyan Wang, Shuo Liang, Wenjie Zhang, Linchuan Li, Qian Xu, Bowen Shi, Zhiqiang Cheng, Xiang Zhang, Mingwei Zhong, Guangyong Zhang, Sanyuan Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
5-fluorouracil
chemoresistance
CD147
glycolipid metabolism reprogramming
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.813852/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.813852/full

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