Putting on molecular weight: Enabling cryo-EM structure determination of sub-100-kDa proteins

Significant advances in the past decade have enabled high-resolution structure determination of a vast variety of proteins by cryogenic electron microscopy single particle analysis. Despite improved sample preparation, next-generation imaging hardware, and advanced single particle analysis algorithm...

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Bibliographic Details
Main Authors: Koen Wentinck, Christos Gogou, Dimphna H. Meijer
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Structural Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X22000290