Involvement of Histone Lysine Crotonylation in the Regulation of Nerve-Injury-Induced Neuropathic Pain

Involvement of Histone Lysine Crotonylation in the Regulation of Nerve-Injury-Induced Neuropathic Pain

Histone lysine crotonylation (KCR), a novel epigenetic modification, is important in regulating a broad spectrum of biological processes and various diseases. However, whether KCR is involved in neuropathic pain remains to be elucidated. We found KCR occurs in macrophages, sensory neurons, and satel...

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Bibliographic Details
Main Authors: Yu Zou, Xue-Hui Bai, Ling-Chi Kong, Fei-Fei Xu, Ting-Yu Ding, Peng-Fei Zhang, Fu-Lu Dong, Yue-Juan Ling, Bao-Chun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
histone crotonylation
neuropathic pain
partial infraorbital nerve transection
inflammatory cytokines
chemokine
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.885685/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.885685/full

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