Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer’s disease in Caribbean Hispanics

Abstract Background Genetic studies have primarily been conducted in European ancestry populations, identifying dozens of loci associated with late-onset Alzheimer’s disease (AD). However, much of AD’s heritability remains unexplained; as the prevalence of AD varies across populations, the genetic a...

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Bibliographic Details
Main Authors: Andréa R. V. R. Horimoto, Diane Xue, Timothy A. Thornton, Elizabeth E. Blue
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13195-021-00866-9