The ribosome modulates folding inside the ribosomal exit tunnel
Wruck et al. investigate the folding of the small zinc-finger domain ADR1a inside and at the vestibule of the ribosomal tunnel, using optical tweezers, single-molecule FRET, and molecular dynamics simulations. They find that the ribosomal tunnel accelerates folding while stabilizing the folded state...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-05-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02055-8 |