Molecular mechanisms of cold pain

The sensation of cooling is essential for survival. Extreme cold is a noxious stimulus that drives protective behaviour and that we thus perceive as pain. However, chronic pain patients suffering from cold allodynia paradoxically experience innocuous cooling as excruciating pain. Peripheral sensory...

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Bibliographic Details
Main Authors: Donald Iain MacDonald, John N. Wood, Edward C. Emery
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Neurobiology of Pain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X20300027