88462 Fluconazole distribution in CNS and gynecological tissues in HIV-related cryptococcal meningitis decedents

ABSTRACT IMPACT: Plasma and CSF are not reliable estimates of drug exposure in tissue compartments relevant for treatment and prevention of infectious diseases. OBJECTIVES/GOALS: Globally, high dose fluconazole is widely used in the management of cryptococcal meningitis. While it is known to readily...

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Bibliographic Details
Main Authors: Melanie R. Nicol, Fan Wang, Ambayo Richard, Olivie Carolyne Namuju, Katelyn A Pastick, David R Boulware, David B Meya, Robert Lukande
Format: Article
Language:English
Published: Cambridge University Press 2021-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866121006488/type/journal_article