Drug-induced QT prolongation and torsade de pointes: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System database

Drug-induced QT prolongation and torsade de pointes: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System database

Introduction: Drug-induced QT prolongation and (or) Torsade de Pointes (TdP) is a well-known serious adverse reaction (ADR) for some drugs, but the widely recognized comprehensive landscape of culprit-drug of QT prolongation and TdP is currently lacking.Aim: To identify the top drugs reported in ass...

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Bibliographic Details
Main Authors: Dongxuan Li, Shuang Chai, Hongli Wang, Jie Dong, Chunmeng Qin, Dan Du, Yalan Wang, Qian Du, Songqing Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pharmacology
Subjects:
QT prolongation
torsade de pointes
FDA adverse event reporting system
disproportionality analysis
pharmacovigilance
adverse reaction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1259611/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1259611/full

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