Formal synthesis of bastimolide A using a chiral Horner-Wittig reagent and a bifunctional aldehyde as key building blocks
The macrolide bastimolide A represents an attractive synthetic target due to its promising activity against resistant strains of the malaria pathogen plasmodium falciparum. We report a straightforward formal synthesis of bastimolide A using a Horner-Wittig reagent and an aldehyde derived from the sa...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-03-01
|
| Series: | Tetrahedron Chem |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666951X24000044 |