ARP-1 Regulates the Transcriptional Activity of the Aromatase Gene in the Mouse Brain

An important function of aromatase in the brain is conversion of testosterone secreted from the testis into estradiol. Estradiol produced in the brain is thought to be deeply involved in the formation of sexually dimorphic nuclei and sexual behavior as a neurosteroid. We analyzed the brain-specific...

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Bibliographic Details
Main Authors: Shin-ichiro Honda, Nobuhiro Harada
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00306/full