The Mechanism of Environmental Endocrine Disruptors (DEHP) Induces Epigenetic Transgenerational Inheritance of Cryptorchidism.

Discussion on the role of DEHP in the critical period of gonadal development in pregnant rats (F0), studied the evolution of F1-F4 generation of inter-generational inheritance of cryptorchidism and the alteration of DNA methylation levels in testis. Pregnant SD rats were randomly divided into two gr...

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Bibliographic Details
Main Authors: Jinjun Chen, Shengde Wu, Sheng Wen, Lianju Shen, Jinpu Peng, Chao Yan, Xining Cao, Yue Zhou, Chunlan Long, Tao Lin, Dawei He, Yi Hua, Guanghui Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126403