Isosorbide Dinitrate Orally Disintegrating Films Cyclodextrins/HPMC Based: Mechanical, Optical, and Physicochemical Studies

Isosorbide Dinitrate Orally Disintegrating Films Cyclodextrins/HPMC Based: Mechanical, Optical, and Physicochemical Studies

Abstract Orally disintegrating films (ODFs) were prepared from hydroxypropyl methylcellulose (HPMC E6 1.5%, 2.0%, and 2.5%), plasticizers ((glycerin (Gly), propylene glycol (PP), or polyethylene glycol (PEG)), and isosorbide dinitrate using the solvent casting method. Design of experiments (DoE) was...

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Bibliographic Details
Main Authors: Larissa Lea da Silva, Marcelo Dutra Duque, Michele Georges Issa, Leticia Norma Carpentieri Rodrigues
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2023-11-01
Series:Brazilian Archives of Biology and Technology
Subjects:
isosorbide dinitrate
cyclodextrins
orally disintegrating films
mechanical properties
desirability function
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100637&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132023000100637&lng=en&tlng=en

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