Roles for BLyS family members in meeting the distinct homeostatic demands of innate and adaptive B cells

B-1 and B-2 B cell populations have different progenitors, receptor diversity, anatomic location, and functions -- suggesting vastly difffering requisites for homeostatic regulation. There is evidence that the BLyS family of cytokines and receptors, key factors in the homeostatic regulation of B-2...

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Bibliographic Details
Main Authors: Michael P. Cancro, Jean L. Scholz, Vishal J. Sindhava
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00037/full