IMPre: an accurate and efficient software for prediction of T- and B-cell receptor germline genes and alleles from rearranged repertoire data

IMPre: an accurate and efficient software for prediction of T- and B-cell receptor germline genes and alleles from rearranged repertoire data

Large-scale study of the properties of T-cell receptor (TCR) and B-cell receptor (BCR) repertoires through next-generation sequencing is providing excellent insights into the understanding of adaptive immune responses. Variable(Diversity)Joining V(D)J germline genes and alleles must be characterized...

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Bibliographic Details
Main Authors: Wei Zhang, I-Ming Wang, Changxi Wang, Liya Lin, Xianghua Chai, Jinghua Wu, Andrew J. Bett, Dhanasekaran Govindarajan, Danilo R. Casimiro, Xiao Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Immunology
Subjects:
monkey
immune repertoire
TRB
IGH
novel germline gene
novel germline allele
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00457/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00457/full

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