Influence of Zika virus 3′-end sequence and nonstructural protein evolution on the viral replication competence and virulence

Influence of Zika virus 3′-end sequence and nonstructural protein evolution on the viral replication competence and virulence

Zika virus (ZIKV) has been circulating in human networks over 70 years since its first appearance in Africa, yet little is known about whether the viral 3′-terminal sequence and nonstructural (NS) protein diverged genetically from ancient ZIKV have different effects on viral replication and virulenc...

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Bibliographic Details
Main Authors: Hae-Gwang Jung, Hee Cho, Minwoo Kim, Haewon Jung, Yeonju Bak, Se-Young Lee, Han Young Seo, Yu-Min Son, Hawon Woo, Gone Yoon, Seong-Jun Kim, Jong-Won Oh
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Emerging Microbes and Infections
Subjects:
Zika virus
infectious cDNA clone
virulence determinant
3′-end sequence variants
nonstructural proteins
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2022.2128433

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https://www.tandfonline.com/doi/10.1080/22221751.2022.2128433

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