Regulation of DNA damage response by trimeric G-proteins
Summary: Upon sensing DNA double-strand breaks (DSBs), eukaryotic cells either die or repair DSBs via one of the two competing pathways, i.e., non-homologous end-joining (NHEJ) or homologous recombination (HR). We show that cell fate after DSBs hinges on GIV/Girdin, a guanine nucleotide-exchange mod...
Asıl Yazarlar: | , , , , , , , , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Elsevier
2023-02-01
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Seri Bilgileri: | iScience |
Konular: | |
Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2589004223000500 |