Pathogen proteins eliciting antibodies do not share epitopes with host proteins: a bioinformatics approach.

The best way to prevent diseases caused by pathogens is by the use of vaccines. The advent of genomics enables genome-wide searches of new vaccine candidates, called reverse vaccinology. The most common strategy to apply reverse vaccinology is by designing subunit recombinant vaccines, which usually...

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Bibliographic Details
Main Authors: Isaac Amela, Juan Cedano, Enrique Querol
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1885212?pdf=render