Role of ox-PAPCs in the differentiation of mesenchymal stem cells (MSCs) and Runx2 and PPARγ2 expression in MSCs-like of osteoporotic patients.

Role of ox-PAPCs in the differentiation of mesenchymal stem cells (MSCs) and Runx2 and PPARγ2 expression in MSCs-like of osteoporotic patients.

BACKGROUND: Mesenchymal stem cells (MSCs) can differentiate into osteoblasts and adipocytes and conditions causing bone loss may induce a switch from the osteoblast to adipocyte lineage. In addition, the expression of Runx2 and the PPARγ2 transcription factor genes is essential for cellular commitme...

Full description

Bibliographic Details
Main Authors: Maria Teresa Valenti, Ulisse Garbin, Andrea Pasini, Mirko Zanatta, Chiara Stranieri, Stefania Manfro, Chiara Zucal, Luca Dalle Carbonare
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108593?pdf=render

Internet

http://europepmc.org/articles/PMC3108593?pdf=render

Similar Items