Calorie restriction and pravastatin administration during pregnancy in obese rhesus macaques modulates maternal and infant metabolism and infant brain and behavioral development

Calorie restriction and pravastatin administration during pregnancy in obese rhesus macaques modulates maternal and infant metabolism and infant brain and behavioral development

BackgroundMaternal obesity has been associated with a higher risk of pregnancy-related complications in mothers and offspring; however, effective interventions have not yet been developed. We tested two interventions, calorie restriction and pravastatin administration, during pregnancy in a rhesus m...

Full description

Bibliographic Details
Main Authors: Yu Hasegawa, Danielle H. J. Kim, Zhichao Zhang, Ameer Y. Taha, John P. Capitanio, Casey E. Hogrefe, Melissa D. Bauman, Mari S. Golub, Judy Van de Water, Catherine A. VandeVoort, Cheryl K. Walker, Carolyn M. Slupsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Nutrition
Subjects:
obesity
pregnancy
gestational weight gain
calorie restriction
pravastatin
infant development
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1146804/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2023.1146804/full

Similar Items