CRISPR/Cas9 and Transgene Verification of Gene Involvement in Unfolded Protein Response and Recombinant Protein Production in Barley Grain

CRISPR/Cas9 and Transgene Verification of Gene Involvement in Unfolded Protein Response and Recombinant Protein Production in Barley Grain

The use of plants as heterologous hosts to produce recombinant proteins has some intriguing advantages. There is, however, the potential of overloading the endoplasmic reticulum (ER) capacity when producing recombinant proteins in the seeds. This leads to an ER-stress condition and accumulating of u...

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Bibliographic Details
Main Authors: Michael Panting, Inger Baeksted Holme, Jón Már Björnsson, Yingxin Zhong, Henrik Brinch-Pedersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Plant Science
Subjects:
barley
unfolded protein response
heterologous expression
recombinant protein
CRISPR
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2021.755788/full

Internet

https://www.frontiersin.org/articles/10.3389/fpls.2021.755788/full

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