Construction of recombinant adenovirus-5 vector to prevent replication-competent adenovirus occurrence

Human adenovirus-5 (hAd5) is an important gene delivery vector, which has been widely used in various fields of biomedicine, such as gene therapy, cancer therapy, and vaccine development. However, replication-competent adenovirus (RCA) generated when adenoviral vectors are prepared in HEK293 cells h...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Wenbo Xie, Yifei Yuan, Bo Liu, Min Liang
स्वरूप: लेख
भाषा:English
प्रकाशित: Frontiers Media S.A. 2023-12-01
श्रृंखला:Acta Virologica
विषय:
ऑनलाइन पहुंच:https://www.frontierspartnerships.org/articles/10.3389/av.2023.11642/full