Construction of recombinant adenovirus-5 vector to prevent replication-competent adenovirus occurrence
Human adenovirus-5 (hAd5) is an important gene delivery vector, which has been widely used in various fields of biomedicine, such as gene therapy, cancer therapy, and vaccine development. However, replication-competent adenovirus (RCA) generated when adenoviral vectors are prepared in HEK293 cells h...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-12-01
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| Series: | Acta Virologica |
| Subjects: | |
| Online Access: | https://www.frontierspartnerships.org/articles/10.3389/av.2023.11642/full |