Bioassay-based Corchorus capsularis L. leaf-derived β-sitosterol exerts antileishmanial effects against Leishmania donovani by targeting trypanothione reductase

Abstract Leishmaniasis, a major neglected tropical disease, affects millions of individuals worldwide. Among the various clinical forms, visceral leishmaniasis (VL) is the deadliest. Current antileishmanial drugs exhibit toxicity- and resistance-related issues. Therefore, advanced chemotherapeutic a...

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Bibliographic Details
Main Authors: Pijush Kanti Pramanik, Sajal Chakraborti, Angshuman Bagchi, Tapati Chakraborti
Format: Article
Language:English
Published: Nature Portfolio 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77066-2