Association of GBA genotype with motor and cognitive decline in Chinese Parkinson’s disease patients

Association of GBA genotype with motor and cognitive decline in Chinese Parkinson’s disease patients

ObjectiveVariants in the glucocerebrosidase (GBA) gene are the most common and significant risk factor for Parkinson’s disease (PD). However, the impact of GBA variants on PD disease progression in the Chinese population remains unclear. This study aimed to explore the significance of GBA status on...

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Bibliographic Details
Main Authors: Jingru Ren, Gaiyan Zhou, Yajie Wang, Ronggui Zhang, Zhiying Guo, Hao Zhou, Huifen Zheng, Yu Sun, Changyan Ma, Ming Lu, Weiguo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
cognitive decline
GBA
longitudinal
motor impairment
Parkinson’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1091919/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1091919/full

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