Effect of perioperative sigh ventilation on postoperative hypoxemia and pulmonary complications after on-pump cardiac surgery (E-SIGHT): study protocol for a randomized controlled trial

Abstract Background Postoperative hypoxemia and pulmonary complications remain a frequent event after on-pump cardiac surgery and mostly characterized by pulmonary atelectasis. Surfactant dysfunction or hyposecretion happens prior to atelectasis formation, and sigh represents the strongest stimulus...

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Bibliographic Details
Main Authors: Zhichang Wang, Qiyu Cheng, Shenglun Huang, Jie Sun, Jingyuan Xu, Jianfeng Xie, Hailong Cao, Fengmei Guo
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-024-08416-y