Mammalian target of rapamycin inhibitors: A paradigm shift in current immunosuppression protocols

Immunosuppression is an obligate necessity in kidney transplant. However, the standard immunosuppression causes chronic deterioration of allograft function over long term use. Mammalian target of rapamycin (mTOR) inhibitors provide an alternative in such scenario. The mTOR inhibitors engage FKBP12 t...

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Bibliographic Details
Main Authors: Indranil Ghosh, Manish Rathi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Transplantation
Subjects:
Online Access:http://www.ijtonline.in/article.asp?issn=2212-0017;year=2016;volume=10;issue=2;spage=33;epage=39;aulast=Ghosh;type=0