The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection

The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection

The ongoing emergence of SARS-CoV-2 virus variants remains a source of concern because it is accompanied by the potential for increased virulence as well as evasion of immunity. Here we show that, although having an almost identical spike gene sequence as another Omicron variant (BA.5.2.1), a BA.4 i...

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Bibliographic Details
Main Authors: Elizabeth R. Davies, Kathryn A. Ryan, Kevin R. Bewley, Naomi S. Coombes, Francisco J. Salguero, Oliver T. Carnell, Sarah Biddlecombe, Michael Charlton, Amy Challis, Eleanor S. Cross, Alastair Handley, Didier Ngabo, Thomas M. Weldon, Yper Hall, Simon G. P. Funnell
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Viruses
Subjects:
SARS-CoV-2
Syrian hamster
animal model
coronavirus
Online Access:https://www.mdpi.com/1999-4915/15/5/1133

Internet

https://www.mdpi.com/1999-4915/15/5/1133

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