H3K27ac nucleosomes facilitate HMGN localization at regulatory sites to modulate chromatin binding of transcription factors

The nucleosome-binding proteins HMGN1 and HMGN2 prefer acetylated nucleosomes at H3K27ac and the loss of this interaction alters binding of transcription factors to chromatin.

Bibliographic Details
Main Authors: Shaofei Zhang, Yuri Postnikov, Alexei Lobanov, Takashi Furusawa, Tao Deng, Michael Bustin
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03099-0