Hydrophobic ion pairing and microfluidic nanoprecipitation enable efficient nanoformulation of a small molecule indolamine 2, 3‐dioxygenase inhibitor immunotherapeutic

Abstract Blockade of programmed cell death‐1 (PD‐1) is a transformative immunotherapy. However, only a fraction of patients benefit, and there is a critical need for broad‐spectrum checkpoint inhibition approaches that both enhance the recruitment of cytotoxic immune cells in cold tumors and target...

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Bibliographic Details
Main Authors: Parisa Badiee, Michelle F. Maritz, Pouya Dehghankelishadi, Nicole Dmochowska, Benjamin Thierry
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10599