A single-molecule view of telomerase regulation at telomeres
Telomerase plays a key role in the immortalization of cancer cells by maintaining telomeres length. Using single-molecule imaging of telomerase RNA molecules in cancer cells, we recently reported novel insights into the role of Cajal bodies in telomerase biogenesis and the regulation of telomerase r...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-11-01
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| Series: | Molecular & Cellular Oncology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/23723556.2020.1818537 |
| _version_ | 1827809368383422464 |
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| author | Pascal Chartrand Agnel Sfeir |
| author_facet | Pascal Chartrand Agnel Sfeir |
| author_sort | Pascal Chartrand |
| collection | DOAJ |
| description | Telomerase plays a key role in the immortalization of cancer cells by maintaining telomeres length. Using single-molecule imaging of telomerase RNA molecules in cancer cells, we recently reported novel insights into the role of Cajal bodies in telomerase biogenesis and the regulation of telomerase recruitment to telomeres. |
| first_indexed | 2024-03-11T22:40:13Z |
| format | Article |
| id | doaj.art-cc2811d2a9944ab4a2317078697ea8ed |
| institution | Directory Open Access Journal |
| issn | 2372-3556 |
| language | English |
| last_indexed | 2024-03-11T22:40:13Z |
| publishDate | 2020-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Molecular & Cellular Oncology |
| spelling | doaj.art-cc2811d2a9944ab4a2317078697ea8ed2023-09-22T09:11:02ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562020-11-017610.1080/23723556.2020.18185371818537A single-molecule view of telomerase regulation at telomeresPascal Chartrand0Agnel Sfeir1Université De MontréalNYU School of MedicineTelomerase plays a key role in the immortalization of cancer cells by maintaining telomeres length. Using single-molecule imaging of telomerase RNA molecules in cancer cells, we recently reported novel insights into the role of Cajal bodies in telomerase biogenesis and the regulation of telomerase recruitment to telomeres.http://dx.doi.org/10.1080/23723556.2020.1818537telomerasetelomereslive-cell imaging |
| spellingShingle | Pascal Chartrand Agnel Sfeir A single-molecule view of telomerase regulation at telomeres Molecular & Cellular Oncology telomerase telomeres live-cell imaging |
| title | A single-molecule view of telomerase regulation at telomeres |
| title_full | A single-molecule view of telomerase regulation at telomeres |
| title_fullStr | A single-molecule view of telomerase regulation at telomeres |
| title_full_unstemmed | A single-molecule view of telomerase regulation at telomeres |
| title_short | A single-molecule view of telomerase regulation at telomeres |
| title_sort | single molecule view of telomerase regulation at telomeres |
| topic | telomerase telomeres live-cell imaging |
| url | http://dx.doi.org/10.1080/23723556.2020.1818537 |
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