THE ROLE OF LET-7/HMGA2 LINKAGE IN THE PATHOGENESIS AND PROGNOSIS OF MYELODYSPLASTIC NEOPLASMS

Introduction: MicroRNAs (miRNAs),are significant regulators of human hematopoietic stem cells. Their deregulation contributes to hematological malignancies.The let-7 family has been found frequently deregulated in malignancies.In MDS various alterations of miRNAs have been reported.High Mobility Gro...

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Main Authors: D. Vlachopoulou, C.-N. Kontandreopoulou, P.T. Diamantopoulos, S. Syriopoulou, C. Stafylidis, P. Katsiampoura, A. Galanopoulos, M. Dimou, P. Panayiotidis, N.-A. Viniou
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Leukemia Research Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048924000189