STEAP2 promotes osteosarcoma progression by inducing epithelial–mesenchymal transition via the PI3K/AKT/mTOR signaling pathway and is regulated by EFEMP2

STEAP2 promotes osteosarcoma progression by inducing epithelial–mesenchymal transition via the PI3K/AKT/mTOR signaling pathway and is regulated by EFEMP2

This study was designed to explore the prognostic significance and functionality of STEAP2 (six-transmembrane epithelial antigen of prostate 2) in osteosarcomas and determine whether EFEMP2 (Epidermal growth factor-containing fibulin-like extracellular matrix protein 2) targets STEAP2 to facilitate...

Full description

Bibliographic Details
Main Authors: Dong Zhang, Haitao Liu, Weihua Wang, Gang Xu, Chenxiao Yin, Songgang Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Cancer Biology & Therapy
Subjects:
steap2
osteosarcoma
pi3k/akt/mtor signaling pathway
emt
invasion
metastasis
Online Access:http://dx.doi.org/10.1080/15384047.2022.2136465

Internet

http://dx.doi.org/10.1080/15384047.2022.2136465

Similar Items