Influence of glutathione S‐transferases (GSTM1, GSTT1, and GSTP1) genetic polymorphisms and smoking on susceptibility risk of chronic myeloid leukemia and treatment response

Influence of glutathione S‐transferases (GSTM1, GSTT1, and GSTP1) genetic polymorphisms and smoking on susceptibility risk of chronic myeloid leukemia and treatment response

Abstract Background Glutathione S‐transferases (GSTs) polymorphisms may impact on chronic myeloid leukemia (CML) risk or heterogeneous responses to Imatinib mesylate (IM). The aim of this study was to evaluate the correlation between GSTs polymorphisms and CML risk, treatment response. Methods We ge...

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Bibliographic Details
Main Authors: Golale Rostami, Dlnya Assad, Fatemeh Ghadyani, Mohammad Hamid, Amirhossien Karami, Hasan Jalaeikhoo, Ramezan Ali Kalahroodi
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
chronic myeloid leukemia
genetic polymorphisms
glutathione S‐transferases
smoking status
treatment responses
Online Access:https://doi.org/10.1002/mgg3.717

Internet

https://doi.org/10.1002/mgg3.717

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