Oral Administration of Recombinant Saccharomyces boulardii Expressing Ovalbumin-CPE Fusion Protein Induces Antibody Response in Mice

Oral Administration of Recombinant Saccharomyces boulardii Expressing Ovalbumin-CPE Fusion Protein Induces Antibody Response in Mice

Saccharomyces boulardii, a subspecies of Saccharomyces cerevisiae, is a well-known eukaryotic probiotic with many benefits for human health. In the present study, a recombinant strain of S. boulardii was prepared to use as a potential oral vaccine delivery vehicle. In this sense, a ura3 auxotroph st...

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Bibliographic Details
Main Authors: Ghasem Bagherpour, Hosnie Ghasemi, Bahare Zand, Najmeh Zarei, Farzin Roohvand, Esmat M. Ardakani, Mohammad Azizi, Vahid Khalaj
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Microbiology
Subjects:
Saccharomyces boulardii
antigen delivery
recombinant ovalbumin
Clostridium perfringens enterotoxin
mucosal immunity
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00723/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00723/full

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